SMART Chart Webinar Series: GC-MS

Gas Chromatography-Mass Spectrometry (GC-MS)


Let's take a deeper dive into our SMART Chart!

Gas Chromatography-Mass Spectrometry (GC-MS) is an analytical technique which allows for the identification of specific molecules by combining the features of gas chromatography to separate chemical mixtures and mass spectrometry to identify the components. This enables the separation of complex matrixes to identify trace differences and potential compounds of interest. GC-MS analyses can be performed on liquids, gases or solids to detect volatile or semi-volatile species. The most common detection analysis is by the direct injection of a liquid or gas. However, EAG is equipped with techniques which allow for solids to be analyzed by either solvent extraction, outgassing (thermal desorption) or pyrolysis. Many other sample preparation and sampling methods can be utilized, such as: derivatization, static headspace, purge & trap, and solid phase microextraction (SPME) which can be applied based on the sample type and species of interest.

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About the Presenters:

M CrisalliMeredith Crisalli, Ph.D. GC-MS Scientist
Meredith has over a decade of GC and GC-MS experience. Before joining EAG in 2018, she worked as an analytical chemist in internal labs for biofuels, novel inorganic species and semiconductor precursors. At EAG, Dr. Crisalli is applying her experience to new client concerns focusing on contamination, purification, and outgassing materials and epoxies.


shaun-Shaun Loeffelman, M.S., Manager of Analytical Services
Shaun Loeffelman has over ten years of experience with GC-MS for a wide array of sample types and applications. He worked for three years as a Forensic Scientist for the Nebraska State Patrol Crime Laboratory where he analyzed samples for the presence of controlled substances. He is celebrating ten years at EAG.


In this webinar we will cover:

  • Principles/overview of GC-MS
  • Real-world examples
  • Strengths and limitations
  • Complementary techniques